To Design a Novel Protein -A Concieve-Design-Build-Operate Expereince in Molecular Biotechnology at Linköping University

To Design a Novel Protein -A Concieve-Design-Build-Operate Expereince in Molecular Biotechnology at Linköping University

U. Carlsson, T. Magnusson, L. Mårtensson, M. Sunnerhagen, M. Svensson, L. Tibell (2006).  To Design a Novel Protein -A Concieve-Design-Build-Operate Expereince in Molecular Biotechnology at Linköping University. 4.

To practice Bioengineering, from idea to product, requires extensive laboratory efforts, and is seldom possible to do within the frame of a single lab course. To allow for the students to develop such expertise, we have designed an extended CDIO project, which is performed over three subsequent disciplinary linked courses: Gene Technology, Biomeasurement Technologies and Protein Engineering. In this CDIO project, the students themselves create, clone, express and functionally evaluate a mutant protein of medical relevance. Half of the ~60 students performed the functional evaluation as a self-directed laboratory project in close connection to a parallel course in Project Organization, whereas the other half functionally evaluated their proteins in a teacher-directed lab course. Higher-order cognitive skills in laboratory learning as judged by a Perry evaluation were improved during the project for all students, but in particular for those who performed the self-directed evaluation. Furthermore, the students judged their own professional competence to be significantly increased as a result of their taking part in the CDIO project.

2nd International CDIO Conference, Linköping University, Linköping, Sweden, 13 to 14 June 2006

Authors (New): 
Uno Carlsson
Thomas Magnusson
Lars-Göran Mårtensson
Maria Sunnerhagen
Magdalena Svensson
Lena Tibell
Pages: 
4
Affiliations: 
Linköping University, Linköping, Sweden
Keywords: 
Bioengineering
CDIO
Directed self-learning
Year: 
2006
Reference: 
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