Teaching Measurement Principles in Context: An Instrumentation Laboratory for Biological Engineers

The Course (20.309): Laboratory Fundamentals in Biological Engineering II

Biological Instrumentation and Measurement

– advanced undergraduate laboratory

– modular

• electronics – DNA melting curves analysis

• mechanics – AFM

• optics – fluorescence microscopy, optical trapping

– modules based on measurement systems

20.309 Intellectual core

– Signals and systems

• time/frequency (elec.) & spatial domain (imaging)

• correlation and convolution (elec.), image processing

(optics)

– Fourier techniques

• time/frequency (elec./mech.) & spatial domains (optics)

– Fundamental limits of detection

• position/force detection (mechanics) & resolution (optics)