Faculty of Mass Communication Technology (MCT) at Rajamangala University of Technology Thanyaburi (RMUTT) has adopted CDIO framework as a context for producing professional hands-on graduates since 2015. MCT faculty has adopted CDIO framework in curriculum development for all six programs; namely, Multimedia, Digital Media, Television and Radio, Photography and Cinematography, Advertisement and Public Relations, and Digital Printing and Packaging Technology. Curriculum development process consisted of (1) a stakeholder survey focusing on future of the world of professional work (2) an implementation of CDIO standard 2 to identify program outcome and graduate attributes and (3) an implementation of CDIO standard 3 for integrated curriculum. The introductory course for each program was introduced to the first year students. With a support from the university, a major renovation of workspace and laboratories was undertaken. The state of the art workspaces supporting students’ learning experiences are studio, theatre, render farm lab, 7.1 sound studio, stop motion studio, printing house, TV master control room, and fabrication laboratory. This paper showed similarities and differences of six programs when implementing CDIO concept. Program self-assessment regarding CDIO 12 standards revealed a high commitment to continuous improvement for quality of education.